Application of Methylprednisolone Sodium Succinate Combined with Tropisetron in Prevention of Nausea and Vomiting under Microvascular Decompression of Hemifacial Spasm / 中国医学科学院学报

Objective To evaluate the effect of methylprednisolone sodium succinate combined with tropisetron on postoperative nausea and vomiting(PONV)under microvascular decompression of hemifacial spasm.Methods From January to June 2019,485 patients undergoing microvascular decompression for facial spasm at Department of Neurosurgery,Peking University People's Hospital were randomly assigned into two groups with random number table method.For group A(n=242),2 ml saline was administrated by intravenous drip before induction and 5 mg tropisetron after operation.For group B(n=243),40 mg methylprednisolone sodium succinate was administrated by intravenous drip before induction and 5 mg tropisetron after operation.The anesthesia time,operation time,and incidence of PONV in 0-24 h and 24-48 h were recorded for the comparison of the remedial treatment rate of nausea and vomiting between the two groups.Results There was no significant difference in age,gender,smoking history,body mass index value,American Society of Anesthesiologists score,medical history,surgical side,PONV history,operation time or anesthesia time between the two groups(all P > 0.05).The incidence of PONV in group A was 35.5% and 18.2% during 0-24 h and 24-48 h,respectively,which was significantly higher than that(18.5%,χ

Clinical Application of New Antiepileptic Drugs / 中国医学科学院学报

Epilepsy has high incidence and complex etiologies,and its treatment remains challenging.For around 70% of people with epilepsy,seizures can be controlled after proper antiepileptic treatment.The availability of some new antiepileptic drugs in recent years has offered new options for epileptic patients.A solid knowledge on the pharmacokinetics,efficacy,and tolerability profiles of these new antiepileptic drugs will help to provide safe,proper,reasonable,and standardized treatment for patients.

An investigation on the resource status of mental health service organizations in Hangzhou / 预防医学

Objective To learn the current status of the resources of mental health organizations in Hangzhou,and to provide evidence for the government departments to formulate plans and to allocate mental health service resources reasonably.Methods The investigation was conducted by Hangzhou Mental Health Office,which compiled and issued "Hangzhou Mental Health Services Questionnaire",and reported by the District Mental Health Office.Data was statistically analyzed on mental health service organizations,beds,outpatient visits,hospitalization visits and spiritual practitioners in 2015.Results Totally 29 organizations,11 rehabilitation centers and 128 community occupation therapy institutions carried out mental health services,and 24 medical organizations and all the rehabilitation centers were located in the main city.A total of 3,079 beds in these organizations were recorded,that is to say,each 10,000 people own 3.54 beds with 3.86 beds per 10,000 people in the main city and 2.24 beds per 10,000 people in the disfrict.The bed utilization rate was over 80％.There were 467 psychiatrists (including the assistants) and 833 psychiatric nurses in Hangzhou,in other words,there were 5.37 psychiatrists and 9.57 psychiatric nurses serving every 100,000 people.The ratio of beds and personnel of the mental health service was 1:0.42.Conclusion The mental health service resources in the urban was better than the county,but the distribution of service resources among different areas was not balanced.Although the level of the density of beds,and the number of people practicing were high,that still can not meet the needs of society.